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PN-Scoring

Shortly before the fusion of the maternal and paternal chromosomes (pronucleus stadium/PN) the distribution pattern of the nucleoli (precursor bodies) can be determined through an expensive digitalised, image-generating method. The nucleoli are concentrations of the genetic material in the pronucleus stage. The distribution pattern of these nucleoli allows inferences on the future embryo’s development potential. By selecting the fertilised eggs with optimum distribution pattern it is possible to choose the cells with the best prognosis.